DNA (cytosine-5)-methyltransferase 3B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UBC3. Use UniProt Q9UBC3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UBC3 as the stable identity anchor, then attach disease evidence before program review.
DNA (cytosine-5)-methyltransferase 3B
Review this target as DNA (cytosine-5)-methyltransferase 3B, mapped to UniProt Q9UBC3. Sequence length is 853 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA (cytosine-5)-methyltransferase 3B as ChEMBL target CHEMBL6095, mapped to UniProt Q9UBC3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DNA (cytosine-5)-methyltransferase 3B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UBC3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA (cytosine-5)-methyltransferase 3B |
| UniProt Accession | Q9UBC3 |
| Component Type | Protein |
| Sequence Length | 853 aa |
DNA (cytosine-5)-methyltransferase 3B
Review this target as DNA (cytosine-5)-methyltransferase 3B, mapped to UniProt Q9UBC3. Sequence length is 853 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL418052 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL555257 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL5178532 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL552309 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL557902 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL2106789 | 6.3 | IC50 | 500.0 | Clinical |
| CHEMBL555352 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL560105 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL1564869 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL560505 | 6.05 | IC50 | 900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 29 | 22 | 5.3 |
| cell-based format | 17 | 50 | 5.3 |
| assay format | 2 | 2 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 6.0 |