Tyrosine-protein phosphatase non-receptor type 9 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P43378. Use UniProt P43378 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P43378 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein phosphatase non-receptor type 9
Review this target as Tyrosine-protein phosphatase non-receptor type 9, mapped to UniProt P43378. Sequence length is 593 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein phosphatase non-receptor type 9 as ChEMBL target CHEMBL6117, mapped to UniProt P43378. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein phosphatase non-receptor type 9 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P43378 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein phosphatase non-receptor type 9 |
| UniProt Accession | P43378 |
| Component Type | Protein |
| Sequence Length | 593 aa |
Tyrosine-protein phosphatase non-receptor type 9
Review this target as Tyrosine-protein phosphatase non-receptor type 9, mapped to UniProt P43378. Sequence length is 593 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3978384 | 7.47 | Ki | 34.0 | Preclinical |
| CHEMBL3978384 | 7.12 | IC50 | 75.0 | Preclinical |
| CHEMBL3949280 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL4569405 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL2396718 | 6.23 | IC50 | 590.0 | Preclinical |
| CHEMBL3917014 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL2316908 | 5.97 | IC50 | 1070.0 | Preclinical |
| CHEMBL2316906 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL4530344 | 5.62 | IC50 | 2400.0 | Preclinical |
| CHEMBL2396719 | 5.52 | IC50 | 3000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 19 | 5.3 |
| assay format | 5 | 21 | 5.2 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |