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Target Snapshot

CHEMBL612600 Target Snapshot

Helicobacter pylori · ORGANISM · Helicobacter pylori

Back to Search Search this target Browse approvals Evidence Card
1,057Compounds
714Assays
0Approved Drugs
9.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Helicobacter pylori as ChEMBL target CHEMBL612600. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Helicobacter pylori
ORGANISM · Helicobacter pylori
As of 2026-09-14
ChEMBL target ID
CHEMBL612600
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Helicobacter pylori still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameHelicobacter pylori
Target TypeORGANISM
OrganismHelicobacter pylori
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHelicobacter pylori
UniProt AccessionN/A

Helicobacter pylori

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Helicobacter pylori.

Review nameHelicobacter pylori
OrganismHelicobacter pylori
Assay Mix

Activity Type Distribution

IC509.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1231347 7.92 IC50 12.0 Preclinical
CHEMBL1254452 6.58 IC50 260.0 Preclinical
CHEMBL4850568 5.96 IC50 1100.0 Preclinical
CHEMBL4461488 5.75 IC50 1800.0 Preclinical
CHEMBL4534412 4.79 IC50 16100.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
2
5.5
0
6.0
1
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

716
Total Assays
6
Tested Compounds
2
Assay Types
Functional — 676 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 647 6 6.2
assay format 27 0 —
cell-based format 2 0 —
ADME — 40 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 40 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine