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Target Snapshot

CHEMBL612647 Target Snapshot

Nakaseomyces glabratus · ORGANISM · Nakaseomyces glabratus

Back to Search Search this target Browse approvals Evidence Card
5,635Compounds
1,632Assays
7Approved Drugs
332.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Nakaseomyces glabratus as ChEMBL target CHEMBL612647. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Nakaseomyces glabratus
ORGANISM · Nakaseomyces glabratus
As of 2026-09-14
ChEMBL target ID
CHEMBL612647
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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Preferred NameNakaseomyces glabratus
Target TypeORGANISM
OrganismNakaseomyces glabratus
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNakaseomyces glabratus
UniProt AccessionN/A

Nakaseomyces glabratus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Nakaseomyces glabratus.

Review nameNakaseomyces glabratus
OrganismNakaseomyces glabratus
Clinical Profile

Clinical Phase Distribution

7
Approved
1
Phase II
Assay Mix

Activity Type Distribution

IC50328.0
EC504.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL453196 8.6 IC50 2.5 Preclinical
CHEMBL1630575 7.3 IC50 50.0 Approved
CHEMBL91 6.92 IC50 120.0 Approved
CHEMBL4061332 6.89 IC50 130.0 Preclinical
CHEMBL267345 6.55 IC50 280.0 Approved
CHEMBL175633 6.19 IC50 650.0 Clinical
CHEMBL157101 6.16 IC50 700.0 Approved
CHEMBL2063002 6.0 IC50 1000.0 Preclinical
CHEMBL64391 5.43 IC50 3740.0 Approved
CHEMBL4062764 5.0 IC50 10000.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
0
5.5
5
6.0
3
6.5
1
7.0
0
7.5
0
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CASPOFUNGIN
CHEMBL1630575
Approved 2001
Properties Compare Identifier
KETOCONAZOLE
CHEMBL157101
Approved 1981
Properties Compare Identifier
MICONAZOLE
CHEMBL91
Approved 1974
Properties Compare Identifier
AMPHOTERICIN B
CHEMBL267345
Approved 1964
Properties Compare Identifier
Assay Landscape

Assay Landscape

1,638
Total Assays
27
Tested Compounds
2
Assay Types
Functional — 1,634 assays, 27 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1,608 25 5.8
assay format 26 2 5.0
ADME — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 4 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine