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Target Snapshot

CHEMBL613193 Target Snapshot

H3N2 subtype · ORGANISM · H3N2 subtype

188Compounds
38Assays
6Approved Drugs
257.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats H3N2 subtype as ChEMBL target CHEMBL613193. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
H3N2 subtype
ORGANISM · H3N2 subtype
As of 2026-09-13
ChEMBL target ID
CHEMBL613193
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether H3N2 subtype still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelH3N2 subtype
UniProt AccessionN/A

H3N2 subtype

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as H3N2 subtype.

Review nameH3N2 subtype
OrganismH3N2 subtype
Clinical Profile

Clinical Phase Distribution

6
Approved
Assay Mix

Activity Type Distribution

IC5040.0
EC50217.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL959 7.29 EC50 51.0 Approved
CHEMBL2151338 7.14 EC50 72.0 Preclinical
CHEMBL577521 6.7 EC50 200.0 Preclinical
CHEMBL1275696 6.47 EC50 340.0 Preclinical
CHEMBL2151345 6.44 EC50 360.0 Preclinical
CHEMBL660 6.4 EC50 400.0 Approved
CHEMBL2207649 6.27 EC50 540.0 Preclinical
CHEMBL2151341 6.17 EC50 680.0 Preclinical
CHEMBL1229 6.1 EC50 800.0 Approved
CHEMBL4279779 6.04 EC50 920.0 Preclinical
Distribution

pChEMBL Value Distribution

43
5.0
34
5.5
14
6.0
6
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

OSELTAMIVIR
CHEMBL1229
Approved 1999
RIMANTADINE
CHEMBL959
Approved 1993
AMANTADINE
CHEMBL660
Approved 1968
Assay Landscape

Assay Landscape

38
Total Assays
85
Tested Compounds
1
Assay Types
Functional — 38 assays, 85 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 38 85 5.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine