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Target Snapshot

CHEMBL613205 Target Snapshot

Human papillomavirus type 16 · ORGANISM · Human papillomavirus type 16

101Compounds
10Assays
1Approved Drugs
101.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Human papillomavirus type 16 as ChEMBL target CHEMBL613205. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Human papillomavirus type 16
ORGANISM · Human papillomavirus type 16
As of 2026-09-14
ChEMBL target ID
CHEMBL613205
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Human papillomavirus type 16 still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHuman papillomavirus type 16
UniProt AccessionN/A

Human papillomavirus type 16

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Human papillomavirus type 16.

Review nameHuman papillomavirus type 16
OrganismHuman papillomavirus type 16
Clinical Profile

Clinical Phase Distribution

1
Approved
1
Phase II
Assay Mix

Activity Type Distribution

IC50101.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL551051 8.3 IC50 5.0 Preclinical
CHEMBL555599 8.3 IC50 5.0 Preclinical
CHEMBL550359 8.1 IC50 8.0 Preclinical
CHEMBL553413 8.1 IC50 8.0 Preclinical
CHEMBL570302 8.1 IC50 8.0 Preclinical
CHEMBL551308 8.0 IC50 10.0 Preclinical
CHEMBL561455 8.0 IC50 10.0 Preclinical
CHEMBL558111 7.77 IC50 17.0 Preclinical
CHEMBL527616 7.75 IC50 18.0 Preclinical
CHEMBL563970 7.75 IC50 18.0 Preclinical
Distribution

pChEMBL Value Distribution

12
5.0
15
5.5
16
6.0
8
6.5
6
7.0
12
7.5
7
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CYCLOSPORINE
CHEMBL160
Approved 1983
Assay Landscape

Assay Landscape

10
Total Assays
93
Tested Compounds
1
Assay Types
Functional — 10 assays, 93 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 10 93 6.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine