MDCK · CELL-LINE · Canis lupus familiaris
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MDCK
Review this target as MDCK.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MDCK as ChEMBL target CHEMBL614068. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MDCK |
| Target Type | CELL-LINE |
| Organism | Canis lupus familiaris |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as MDCK.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL373114 | 7.65 | IC50 | 22.5 | Preclinical |
| CHEMBL222813 | 7.4 | EC50 | 40.0 | Approved |
| CHEMBL4566346 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL53463 | 6.37 | IC50 | 430.0 | Approved |
| CHEMBL334007 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL3609556 | 5.97 | IC50 | 1070.0 | Preclinical |
| CHEMBL660 | 5.96 | EC50 | 1100.0 | Approved |
| CHEMBL463763 | 5.92 | IC50 | 1200.0 | Clinical |
| CHEMBL295380 | 5.75 | EC50 | 1800.0 | Preclinical |
| CHEMBL3609562 | 5.73 | IC50 | 1870.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1,057 | 159 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 188 | 62 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 95 | 5 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |