ZR-75-1 · CELL-LINE · Homo sapiens
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ZR-75-1
Review this target as ZR-75-1.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ZR-75-1 as ChEMBL target CHEMBL614393. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | ZR-75-1 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as ZR-75-1.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL67 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL2441610 | 9.35 | IC50 | 0.45 | Preclinical |
| CHEMBL3128043 | 9.31 | IC50 | 0.49 | Preclinical |
| CHEMBL3037931 | 9.28 | IC50 | 0.52 | Preclinical |
| CHEMBL2441607 | 9.15 | IC50 | 0.71 | Preclinical |
| CHEMBL5712048 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL5712063 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL4795065 | 8.3 | EC50 | 5.0 | Preclinical |
| CHEMBL107 | 8.22 | EC50 | 6.0 | Approved |
| CHEMBL428647 | 8.21 | IC50 | 6.2 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 270 | 180 | 6.3 |
| organism-based format | 11 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 8 | 7.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |