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Target Snapshot

CHEMBL615051 Target Snapshot

Lassa virus · ORGANISM · Mammarenavirus lassaense

Back to Search Search this target Browse approvals Evidence Card
211Compounds
24Assays
1Approved Drugs
210.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Lassa virus as ChEMBL target CHEMBL615051. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Lassa virus
ORGANISM · Mammarenavirus lassaense
As of 2026-09-14
ChEMBL target ID
CHEMBL615051
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Lassa virus still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameLassa virus
Target TypeORGANISM
OrganismMammarenavirus lassaense
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelLassa virus
UniProt AccessionN/A

Lassa virus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Lassa virus.

Review nameLassa virus
OrganismMammarenavirus lassaense
Clinical Profile

Clinical Phase Distribution

1
Approved
1
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC5020.0
EC50190.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2315146 9.8 EC50 0.16 Preclinical
CHEMBL2315149 9.8 EC50 0.16 Preclinical
CHEMBL4852422 9.54 EC50 0.29 Preclinical
CHEMBL4851799 9.49 EC50 0.32 Preclinical
CHEMBL2435292 9.47 EC50 0.34 Preclinical
CHEMBL2435318 9.47 EC50 0.34 Preclinical
CHEMBL4856859 9.4 EC50 0.4 Preclinical
CHEMBL4858248 9.38 EC50 0.42 Preclinical
CHEMBL4852706 9.25 EC50 0.56 Preclinical
CHEMBL4871373 9.19 EC50 0.65 Preclinical
Distribution

pChEMBL Value Distribution

6
5.0
18
5.5
24
6.0
18
6.5
19
7.0
24
7.5
29
8.0
28
8.5
17
9.0
3
9.5
pChEMBL
Assay Landscape

Assay Landscape

24
Total Assays
184
Tested Compounds
1
Assay Types
Functional — 24 assays, 184 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 22 183 7.5
assay format 1 1 8.8
cell-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine