Transporter · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q63380. Use UniProt Q63380 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63380 as the stable identity anchor, then attach disease evidence before program review.
Transporter
Review this target as Transporter, mapped to UniProt Q63380. Sequence length is 617 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transporter as ChEMBL target CHEMBL6184, mapped to UniProt Q63380. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Transporter is the right protein anchor across sources, using UniProt Q63380 as the stable mapping.
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| Preferred Name | Transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63380 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transporter |
| UniProt Accession | Q63380 |
| Component Type | Protein |
| Sequence Length | 617 aa |
Transporter
Review this target as Transporter, mapped to UniProt Q63380. Sequence length is 617 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL608151 | 9.87 | Ki | 0.1349 | Preclinical |
| CHEMBL14370 | 9.16 | Ki | 0.69 | Approved |
| CHEMBL72 | 9.11 | Ki | 0.78 | Approved |
| CHEMBL393236 | 9.08 | Ki | 0.84 | Preclinical |
| CHEMBL1173532 | 8.6 | Ki | 2.512 | Preclinical |
| CHEMBL1175 | 8.52 | Ki | 3.0 | Approved |
| CHEMBL180101 | 8.51 | IC50 | 3.1 | Clinical |
| CHEMBL552338 | 8.41 | Ki | 3.9 | Preclinical |
| CHEMBL273575 | 8.4 | Ki | 4.0 | Approved |
| CHEMBL641 | 8.4 | Ki | 4.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 11 | 135 | 6.3 |
| single protein format | 10 | 56 | 6.3 |
| assay format | 5 | 51 | 5.1 |
| cell membrane format | 5 | 35 | 5.6 |
| subcellular format | 4 | 3 | 6.0 |
| cell-based format | 2 | 8 | 7.8 |