Assay Detail
Binding
CHEMBL1006040
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human muscarinic M5 receptor expressed in insect Sf9 cells
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Muscarinic acetylcholine receptor M5 (CHEMBL2035) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Nocardimicins A, B, C, D, E, and F, siderophores with muscarinic M3 receptor inhibiting activity from Nocardia sp. TP-A0674.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.79 | 5.79 |
| Ki | 1 | 5.93 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL499519 | NOCARDIMICIN B | — | 2 | 5.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL499519 | NOCARDIMICIN B | Ki | = | 1180.0 | nM | 5.93 |
| CHEMBL499519 | NOCARDIMICIN B | IC50 | = | 1640.0 | nM | 5.79 |