Assay Detail
Binding
CHEMBL1007515
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Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.04 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL468498 | — | — | 1 | 6.04 |
| CHEMBL523716 | — | — | 1 | - |
| CHEMBL511555 | — | — | 1 | - |
| CHEMBL466462 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL468498 | — | Ki | = | 919.0 | nM | 6.04 |
| CHEMBL523716 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL511555 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL466462 | — | Ki | > | 10000.0 | nM | - |