Assay Detail
Functional
CHEMBL1007828
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Cytotoxicity against mouse P388 cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New nardosinanes and 19-oxygenated ergosterols from the soft coral Nephthea armata collected in Taiwan.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.90 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1237054 | PLICAMYCIN | 4.0 | 1 | 7.00 |
| CHEMBL463369 | ARMATINOL B | — | 1 | 5.50 |
| CHEMBL462770 | ARMATINOL A | — | 1 | 5.21 |
| CHEMBL505192 | ARMATIN A | — | 1 | - |
| CHEMBL510935 | — | — | 1 | - |
| CHEMBL454540 | ARMATIN E | — | 1 | - |
| CHEMBL455764 | ARMATIN D | — | 1 | - |
| CHEMBL456746 | ARMATIN C | — | 1 | - |
| CHEMBL456745 | ARMATIN B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1237054 | PLICAMYCIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL463369 | ARMATINOL B | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL462770 | ARMATINOL A | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL505192 | ARMATIN A | IC50 | > | 50000.0 | nM | - |
| CHEMBL510935 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL454540 | ARMATIN E | IC50 | > | 50000.0 | nM | - |
| CHEMBL455764 | ARMATIN D | IC50 | > | 50000.0 | nM | - |
| CHEMBL456746 | ARMATIN C | IC50 | > | 50000.0 | nM | - |
| CHEMBL456745 | ARMATIN B | IC50 | > | 50000.0 | nM | - |