Assay Detail
ADMET
CHEMBL1014597
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Inhibition of CYP3A4
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Pyridine-3-carboxamides as novel CB(2) agonists for analgesia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 16 | 4.22 | 4.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL520413 | — | — | 1 | 4.24 |
| CHEMBL466191 | — | — | 1 | 4.24 |
| CHEMBL465470 | — | — | 1 | 4.19 |
| CHEMBL517646 | — | — | 1 | - |
| CHEMBL480398 | — | — | 1 | - |
| CHEMBL479628 | — | — | 1 | - |
| CHEMBL465460 | — | — | 1 | - |
| CHEMBL465638 | — | — | 1 | - |
| CHEMBL480399 | — | — | 1 | - |
| CHEMBL480212 | — | — | 1 | - |
| CHEMBL480213 | — | — | 1 | - |
| CHEMBL480214 | — | — | 1 | - |
| CHEMBL518619 | — | — | 1 | - |
| CHEMBL482186 | — | — | 1 | - |
| CHEMBL481586 | — | — | 1 | - |
| CHEMBL481398 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL520413 | — | IC50 | = | 57000.0 | nM | 4.24 |
| CHEMBL466191 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL465470 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL517646 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL480398 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL479628 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL465460 | — | IC50 | - | — | - | |
| CHEMBL465638 | — | IC50 | - | — | - | |
| CHEMBL480399 | — | IC50 | - | — | - | |
| CHEMBL480212 | — | IC50 | - | — | - | |
| CHEMBL480213 | — | IC50 | - | — | - | |
| CHEMBL480214 | — | IC50 | - | — | - | |
| CHEMBL518619 | — | IC50 | - | — | - | |
| CHEMBL482186 | — | IC50 | - | — | - | |
| CHEMBL481586 | — | IC50 | - | — | - | |
| CHEMBL481398 | — | IC50 | - | — | - |