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Assay Detail

CHEMBL1015122

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to delta opioid receptor in rat brain membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Brain
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL269)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Ligand binding to nucleic acids and proteins: Does selectivity increase with strength?
Schneider HJ.
Eur J Med Chem (2008) 43 : 2307 -2315
PubMed 18403056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.38 9.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL567175 NALTRINDOLE 1 9.66
CHEMBL401093 OXYMORPHINDOLE 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL567175 NALTRINDOLE Ki = 0.22 nM 9.66
CHEMBL401093 OXYMORPHINDOLE Ki = 0.8 nM 9.10