Assay Detail
Binding
CHEMBL1022294
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant FAAH expressed in HEK293 cells by [3H]anandamide carbon filtration assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of benzothiazole-based analogues as novel, potent, and selective fatty acid amide hydrolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.04 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL460340 | — | — | 1 | 7.96 |
| CHEMBL367966 | — | — | 1 | 7.51 |
| CHEMBL184238 | URB-597 | 1.0 | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL460340 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL367966 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL184238 | URB-597 | IC50 | = | 2187.0 | nM | 5.66 |