Assay Detail
Functional
CHEMBL1024115
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus (CHEMBL613758) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus |
Publication
Current developments in the discovery and design of new drug candidates from plant natural product leads.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 11 | 7.65 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269559 | — | — | 1 | 9.40 |
| CHEMBL68956 | SUKSDORFIN | — | 1 | 5.89 |
| CHEMBL515928 | GOMISIN G | — | 1 | - |
| CHEMBL475880 | SCHISANTHERIN D | — | 1 | - |
| CHEMBL437412 | SCHISANDRIN C | — | 1 | - |
| CHEMBL513752 | KADSURANIN | — | 1 | - |
| CHEMBL404519 | BEVIRIMAT | 2.0 | 1 | - |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | - |
| CHEMBL448719 | — | — | 1 | - |
| CHEMBL472646 | MORONIC ACID | — | 1 | - |
| CHEMBL431573 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269559 | — | EC50 | = | 0.4 | nM | 9.40 |
| CHEMBL68956 | SUKSDORFIN | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL515928 | GOMISIN G | EC50 | = | 0.006 | ug.mL-1 | - |
| CHEMBL475880 | SCHISANTHERIN D | EC50 | = | 0.5 | ug.mL-1 | - |
| CHEMBL437412 | SCHISANDRIN C | EC50 | = | 1.2 | ug.mL-1 | - |
| CHEMBL513752 | KADSURANIN | EC50 | = | 0.8 | ug.mL-1 | - |
| CHEMBL404519 | BEVIRIMAT | EC50 | < | 0.35 | nM | - |
| CHEMBL168 | OLEANOLIC_ACID | EC50 | = | 1.7 | ug.mL-1 | - |
| CHEMBL448719 | — | EC50 | = | 0.0039 | ug.mL-1 | - |
| CHEMBL472646 | MORONIC ACID | EC50 | < | 0.1 | ug.mL-1 | - |
| CHEMBL431573 | — | EC50 | = | 0.00016 | nM | - |