Assay Detail
Binding
CHEMBL1049572
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Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in HEK293 cells by liquid scintillation counting
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.99 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | — | 1 | 9.10 |
| CHEMBL595449 | — | — | 1 | 8.24 |
| CHEMBL605510 | — | — | 1 | 7.54 |
| CHEMBL604903 | — | — | 1 | 7.31 |
| CHEMBL593613 | — | — | 1 | 6.92 |
| CHEMBL596371 | — | — | 1 | 6.56 |
| CHEMBL593844 | — | — | 1 | 5.94 |
| CHEMBL605307 | — | — | 1 | 5.66 |
| CHEMBL595448 | — | — | 1 | 5.64 |
| CHEMBL595015 | — | — | 1 | - |
| CHEMBL611957 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL595449 | — | IC50 | = | 5.8 | nM | 8.24 |
| CHEMBL605510 | — | IC50 | = | 28.8 | nM | 7.54 |
| CHEMBL604903 | — | IC50 | = | 48.9 | nM | 7.31 |
| CHEMBL593613 | — | IC50 | = | 121.0 | nM | 6.92 |
| CHEMBL596371 | — | IC50 | = | 273.0 | nM | 6.56 |
| CHEMBL593844 | — | IC50 | = | 1139.0 | nM | 5.94 |
| CHEMBL605307 | — | IC50 | = | 2195.0 | nM | 5.66 |
| CHEMBL595448 | — | IC50 | = | 2307.0 | nM | 5.64 |
| CHEMBL595015 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL611957 | — | IC50 | > | 10000.0 | nM | - |