Compound Detail
CHEMBL595448
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Basic Information
| ChEMBL ID | CHEMBL595448 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UKDIWNQPBFBSOR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
364.5
MW (Da)
4.30
ALogP
5
HBA
0
HBD
43.2
PSA (Ų)
0.68
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Delta-type opioid receptor CHEMBL3222 | IC50 | 5.64 | 5.64 | 2307.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Delta-type opioid receptor | IC50 | = | 2307.0 | nM | 5.64 | Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in HEK293 c... | 19646882 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19646882 | 10.1016/j.bmc.2009.07.007 | Unchecked | 2 |
| 19646882 | 10.1016/j.bmc.2009.07.007 | Kappa-type opioid receptor | 1 |
| 19646882 | 10.1016/j.bmc.2009.07.007 | Mu-type opioid receptor | 1 |
| 19646882 | 10.1016/j.bmc.2009.07.007 | Delta-type opioid receptor | 1 |
Data from ChEMBL 36 via Core Engine