Assay Detail
Binding
CHEMBL1049573
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from mouse mu opioid receptor expressed in HEK293 cells by liquid scintillation counting
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.76 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL605510 | — | — | 1 | 6.61 |
| CHEMBL604903 | — | — | 1 | 5.61 |
| CHEMBL596371 | — | — | 1 | 5.61 |
| CHEMBL13470 | SNC-80 | — | 1 | 5.22 |
| CHEMBL593613 | — | — | 1 | - |
| CHEMBL595015 | — | — | 1 | - |
| CHEMBL593844 | — | — | 1 | - |
| CHEMBL611957 | — | — | 1 | - |
| CHEMBL595449 | — | — | 1 | - |
| CHEMBL595448 | — | — | 1 | - |
| CHEMBL605307 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL605510 | — | IC50 | = | 245.0 | nM | 6.61 |
| CHEMBL604903 | — | IC50 | = | 2447.0 | nM | 5.61 |
| CHEMBL596371 | — | IC50 | = | 2435.0 | nM | 5.61 |
| CHEMBL13470 | SNC-80 | IC50 | = | 6066.0 | nM | 5.22 |
| CHEMBL593613 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL595015 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL593844 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL611957 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL595449 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL595448 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL605307 | — | IC50 | > | 10000.0 | nM | - |