Assay Detail
Binding
CHEMBL1055306
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Inhibition of SERT
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Sodium-dependent serotonin transporter (CHEMBL228) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Antagonists of the calcium receptor. 2. Amino alcohol-based parathyroid hormone secretagogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.73 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL180672 | — | — | 1 | 8.70 |
| CHEMBL382741 | — | — | 1 | 8.52 |
| CHEMBL570593 | — | — | 1 | 7.64 |
| CHEMBL486278 | — | — | 1 | 7.21 |
| CHEMBL572163 | — | — | 1 | 7.17 |
| CHEMBL1204009 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL180672 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL382741 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL570593 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL486278 | — | IC50 | = | 61.0 | nM | 7.21 |
| CHEMBL572163 | — | IC50 | = | 68.0 | nM | 7.17 |
| CHEMBL1204009 | — | IC50 | = | 78.0 | nM | 7.11 |