Assay Detail
Binding
CHEMBL1072347
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Binding affinity to FGF2 by surface plasmon-based solution affinity assay
17
Total Activities
17
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 17 | 6.93 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL590011 | — | — | 1 | 7.46 |
| CHEMBL604368 | — | — | 1 | 7.37 |
| CHEMBL4297162 | MUPARFOSTAT SODIUM | -1.0 | 1 | 7.21 |
| CHEMBL604570 | — | — | 1 | 7.14 |
| CHEMBL604366 | — | — | 1 | 7.09 |
| CHEMBL604568 | — | — | 1 | 7.08 |
| CHEMBL2029015 | — | — | 1 | 7.07 |
| CHEMBL603122 | — | — | 1 | 7.02 |
| CHEMBL602307 | — | — | 1 | 6.96 |
| CHEMBL590012 | — | — | 1 | 6.89 |
| CHEMBL589773 | — | — | 1 | 6.89 |
| CHEMBL602114 | — | — | 1 | 6.85 |
| CHEMBL590010 | — | — | 1 | 6.80 |
| CHEMBL602113 | — | — | 1 | 6.80 |
| CHEMBL590013 | — | — | 1 | 6.60 |
| CHEMBL604367 | — | — | 1 | 6.32 |
| CHEMBL604569 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL590011 | — | Kd | = | 35.0 | nM | 7.46 |
| CHEMBL604368 | — | Kd | = | 43.0 | nM | 7.37 |
| CHEMBL4297162 | MUPARFOSTAT SODIUM | Kd | = | 61.0 | nM | 7.21 |
| CHEMBL604570 | — | Kd | = | 73.0 | nM | 7.14 |
| CHEMBL604366 | — | Kd | = | 82.0 | nM | 7.09 |
| CHEMBL604568 | — | Kd | = | 83.0 | nM | 7.08 |
| CHEMBL2029015 | — | Kd | = | 86.0 | nM | 7.07 |
| CHEMBL603122 | — | Kd | = | 95.0 | nM | 7.02 |
| CHEMBL602307 | — | Kd | = | 110.0 | nM | 6.96 |
| CHEMBL590012 | — | Kd | = | 130.0 | nM | 6.89 |
| CHEMBL589773 | — | Kd | = | 129.0 | nM | 6.89 |
| CHEMBL602114 | — | Kd | = | 140.0 | nM | 6.85 |
| CHEMBL590010 | — | Kd | = | 160.0 | nM | 6.80 |
| CHEMBL602113 | — | Kd | = | 160.0 | nM | 6.80 |
| CHEMBL590013 | — | Kd | = | 253.0 | nM | 6.60 |
| CHEMBL604367 | — | Kd | = | 480.0 | nM | 6.32 |
| CHEMBL604569 | — | Kd | = | 550.0 | nM | 6.26 |