Assay Detail
Functional
CHEMBL1072429
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Antioxidant activity assessed as hydroxyl radical scavenging activity by chemiluminescence assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quiquelignan A-H, eight new lignoids from the rattan palm Calamus quiquesetinervius and their antiradical, anti-inflammatory and antiplatelet aggregation activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.84 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL153 | TROLOX | — | 1 | 5.36 |
| CHEMBL590248 | QUIQUELIGNAN E | — | 1 | 5.21 |
| CHEMBL590164 | QUIQUELIGNAN F | — | 1 | 4.91 |
| CHEMBL597904 | QUIQUELIGNAN C | — | 1 | 4.82 |
| CHEMBL590181 | QUIQUELIGNAN G | — | 1 | 4.72 |
| CHEMBL589759 | QUIQUELIGNAN B | — | 1 | 4.70 |
| CHEMBL590185 | QUIQUELIGNAN H | — | 1 | 4.69 |
| CHEMBL590000 | QUIQUELIGNAN D | — | 1 | 4.56 |
| CHEMBL598315 | QUIQUELIGNAN A | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL153 | TROLOX | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL590248 | QUIQUELIGNAN E | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL590164 | QUIQUELIGNAN F | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL597904 | QUIQUELIGNAN C | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL590181 | QUIQUELIGNAN G | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL589759 | QUIQUELIGNAN B | IC50 | = | 19900.0 | nM | 4.70 |
| CHEMBL590185 | QUIQUELIGNAN H | IC50 | = | 20400.0 | nM | 4.69 |
| CHEMBL590000 | QUIQUELIGNAN D | IC50 | = | 27500.0 | nM | 4.56 |
| CHEMBL598315 | QUIQUELIGNAN A | IC50 | = | 27400.0 | nM | 4.56 |