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Quick search ChEMBL 36
Compound Detail

CHEMBL598315

QUIQUELIGNAN A
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CCO[C@@H](c1ccc(O)c(OC)c1)[C@H](CO)Oc1c(OC)cc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1OC

Basic Information

ChEMBL ID CHEMBL598315
Name QUIQUELIGNAN A
Phase Preclinical
Structure Type MOL
InChI Key FEQZBFHFXKCFBZ-PTJQVGQKSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

556.6
MW (Da)
4.05
ALogP
11
HBA
4
HBD
153.4
PSA (Ų)
0.27
QED
2
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C29H32O11
MW 556.56
Aromatic Rings 3
Heavy Atoms 40
NP-Likeness 1.50

Activity Summary

IC50 1 meas. best 4.56

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.56 4.56 27400.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET IC50 = 27400.0 nM 4.56 Antioxidant activity assessed as hydroxyl radical scavenging activity by chemilu... 20056545

Literature References

PubMed DOI Target Context # Activities
20056545 10.1016/j.bmc.2009.12.016 NON-PROTEIN TARGET 3
20056545 10.1016/j.bmc.2009.12.016 RAW264.7 1

Data from ChEMBL 36 via Core Engine