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Assay Detail

CHEMBL1099472

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat FAAH
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL3229)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA.
Bioorg Med Chem Lett (2009) 19 : 6793 -6796
PubMed 19850474 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.11 7.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1079421 PHENMEDIPHAM 1 7.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1079421 PHENMEDIPHAM IC50 = 77.0 nM 7.11