Assay Detail
ADMET
CHEMBL1100451
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Inhibition of CYP2C9
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL372357 | — | — | 1 | 6.08 |
| CHEMBL1088051 | — | — | 1 | 5.77 |
| CHEMBL1085893 | — | — | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL372357 | — | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL1088051 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1085893 | — | IC50 | = | 5400.0 | nM | 5.27 |