Assay Detail
ADMET
CHEMBL1107487
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Inhibition of CYP2C9 by LC/MS method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.35 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1099326 | — | — | 1 | 6.05 |
| CHEMBL1098560 | — | — | 1 | 4.65 |
| CHEMBL1099323 | — | — | 1 | - |
| CHEMBL1099330 | — | — | 1 | - |
| CHEMBL1094348 | — | — | 1 | - |
| CHEMBL1094349 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1099326 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL1098560 | — | IC50 | = | 22500.0 | nM | 4.65 |
| CHEMBL1099323 | — | IC50 | > | 12500.0 | nM | - |
| CHEMBL1099330 | — | IC50 | - | — | - | |
| CHEMBL1094348 | — | IC50 | - | — | - | |
| CHEMBL1094349 | — | IC50 | - | — | - |