Assay Detail
Functional
CHEMBL1112437
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Cytotoxicity against human HCT116 cells after 7 days by methylene blue staining
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Additional insights on the bastadins: isolation of analogues from the sponge Ianthella cf. reticulata and exploration of the oxime configurations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 6 | - | - |
| IC50 | 1 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455487 | BASTADIN 4 | — | 1 | 5.89 |
| CHEMBL506286 | BASTADIN 19 | — | 1 | - |
| CHEMBL1076811 | — | — | 1 | - |
| CHEMBL510730 | BASTADIN 6 | — | 1 | - |
| CHEMBL439151 | BASTADIN 5 | — | 1 | - |
| CHEMBL508830 | — | — | 1 | - |
| CHEMBL505637 | BASTADIN 3 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455487 | BASTADIN 4 | IC50 | = | 1280.0 | nM | 5.89 |
| CHEMBL506286 | BASTADIN 19 | Activity | - | — | - | |
| CHEMBL1076811 | — | Activity | - | — | - | |
| CHEMBL510730 | BASTADIN 6 | Activity | - | — | - | |
| CHEMBL439151 | BASTADIN 5 | Activity | - | — | - | |
| CHEMBL508830 | — | Activity | - | — | - | |
| CHEMBL505637 | BASTADIN 3 | Activity | - | — | - |