Assay Detail
Functional
CHEMBL1115596
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Cytotoxicity against human Jurkat cells after 48 hrs by MTT assay
19
Total Activities
19
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Diterpenoids from the feces of Trogopterus xanthipes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 19 | 5.99 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273862 | HYDROXYCAMPTOTHECIN | 3.0 | 1 | 7.52 |
| CHEMBL197308 | FERRUGINOL | — | 1 | 4.46 |
| CHEMBL1094107 | — | — | 1 | - |
| CHEMBL1094786 | TROGOPTEROID A | — | 1 | - |
| CHEMBL1097039 | MACROPHYNIN E | — | 1 | - |
| CHEMBL1097038 | SEMPERVIROL | — | 1 | - |
| CHEMBL1097036 | — | — | 1 | - |
| CHEMBL1099062 | — | — | 1 | - |
| CHEMBL1097037 | — | — | 1 | - |
| CHEMBL225866 | ISOPIMARANE | — | 1 | - |
| CHEMBL1094092 | AKHDARDIOL | — | 1 | - |
| CHEMBL1094091 | — | — | 1 | - |
| CHEMBL1095397 | TROGOPTEROID G | — | 1 | - |
| CHEMBL1095965 | TROGOPTEROID F | — | 1 | - |
| CHEMBL1095396 | TROGOPTEROID E | — | 1 | - |
| CHEMBL1095306 | TROGOPTEROID D | — | 1 | - |
| CHEMBL1095113 | TROGOPTEROID C | — | 1 | - |
| CHEMBL1095112 | TROGOPTEROID B | — | 1 | - |
| CHEMBL254635 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273862 | HYDROXYCAMPTOTHECIN | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL197308 | FERRUGINOL | IC50 | = | 35100.0 | nM | 4.46 |
| CHEMBL1094107 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL1094786 | TROGOPTEROID A | IC50 | > | 40000.0 | nM | - |
| CHEMBL1097039 | MACROPHYNIN E | IC50 | > | 40000.0 | nM | - |
| CHEMBL1097038 | SEMPERVIROL | IC50 | > | 40000.0 | nM | - |
| CHEMBL1097036 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL1099062 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL1097037 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL225866 | ISOPIMARANE | IC50 | > | 40000.0 | nM | - |
| CHEMBL1094092 | AKHDARDIOL | IC50 | > | 40000.0 | nM | - |
| CHEMBL1094091 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095397 | TROGOPTEROID G | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095965 | TROGOPTEROID F | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095396 | TROGOPTEROID E | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095306 | TROGOPTEROID D | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095113 | TROGOPTEROID C | IC50 | > | 40000.0 | nM | - |
| CHEMBL1095112 | TROGOPTEROID B | IC50 | > | 40000.0 | nM | - |
| CHEMBL254635 | — | IC50 | > | 40000.0 | nM | - |