Assay Detail
Functional
CHEMBL1120574
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP mobilization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Parathyroid hormone/parathyroid hormone-related peptide receptor (CHEMBL1793) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Emerging targets in osteoporosis disease modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.25 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL525610 | TERIPARATIDE | 4.0 | 1 | 9.00 |
| CHEMBL1084168 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL525610 | TERIPARATIDE | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1084168 | — | EC50 | = | 3200.0 | nM | 5.50 |