Assay Detail
ADMET
CHEMBL1120983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.93 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL515252 | — | — | 1 | 7.10 |
| CHEMBL1237210 | — | — | 1 | 5.64 |
| CHEMBL286494 | HYPERICIN | 3.0 | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL515252 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL1237210 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL286494 | HYPERICIN | IC50 | = | 8700.0 | nM | 5.06 |