Assay Detail
Functional
CHEMBL1168874
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Anticancer activity against human OE33 cells after 24 hrs by MTT assay
36
Total Activities
36
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OE33 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 36 | 4.32 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1163275 | — | — | 1 | 4.72 |
| CHEMBL1163848 | — | — | 1 | 4.55 |
| CHEMBL1163780 | — | — | 1 | 4.55 |
| CHEMBL1164313 | — | — | 1 | 4.55 |
| CHEMBL1164872 | — | — | 1 | 4.55 |
| CHEMBL1165527 | — | — | 1 | 4.47 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.46 |
| CHEMBL1163850 | — | — | 1 | 4.44 |
| CHEMBL1164496 | — | — | 1 | 4.44 |
| CHEMBL1165205 | — | — | 1 | 4.40 |
| CHEMBL1165314 | — | — | 1 | 4.35 |
| CHEMBL1164467 | — | — | 1 | 4.35 |
| CHEMBL1164564 | — | — | 1 | 4.33 |
| CHEMBL1163849 | — | — | 1 | 4.28 |
| CHEMBL1164100 | — | — | 1 | 4.26 |
| CHEMBL1165328 | — | — | 1 | 4.26 |
| CHEMBL1165327 | — | — | 1 | 4.25 |
| CHEMBL1164769 | — | — | 1 | 4.21 |
| CHEMBL1164563 | — | — | 1 | 4.20 |
| CHEMBL1163821 | — | — | 1 | 4.20 |
| CHEMBL1164099 | — | — | 1 | 4.19 |
| CHEMBL1163757 | — | — | 1 | 4.19 |
| CHEMBL1165533 | — | — | 1 | 4.18 |
| CHEMBL1164287 | — | — | 1 | 4.18 |
| CHEMBL1165315 | — | — | 1 | 4.18 |
| CHEMBL1163758 | — | — | 1 | 4.17 |
| CHEMBL1163276 | — | — | 1 | 4.15 |
| CHEMBL1164468 | — | — | 1 | 4.14 |
| CHEMBL1164820 | — | — | 1 | 4.11 |
| CHEMBL120568 | VANILLIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1163275 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL1163848 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL1164872 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL1164313 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL1163780 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL1165527 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL140 | CURCUMIN | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL1163850 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL1164496 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL1165205 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL1165314 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL1164467 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL1164564 | — | IC50 | = | 47000.0 | nM | 4.33 |
| CHEMBL1163849 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL1165328 | — | IC50 | = | 55000.0 | nM | 4.26 |
| CHEMBL1164100 | — | IC50 | = | 55000.0 | nM | 4.26 |
| CHEMBL1165327 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL1164769 | — | IC50 | = | 61000.0 | nM | 4.21 |
| CHEMBL1164563 | — | IC50 | = | 63000.0 | nM | 4.20 |
| CHEMBL1163821 | — | IC50 | = | 63000.0 | nM | 4.20 |
| CHEMBL1164099 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL1163757 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL1165533 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL1164287 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL1165315 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL1163758 | — | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL1163276 | — | IC50 | = | 71000.0 | nM | 4.15 |
| CHEMBL1164468 | — | IC50 | = | 73000.0 | nM | 4.14 |
| CHEMBL1164820 | — | IC50 | = | 77000.0 | nM | 4.11 |
| CHEMBL120568 | VANILLIC ACID | IC50 | > | 1000000.0 | nM | - |
| CHEMBL486214 | METHYL VANILLATE | IC50 | > | 100000.0 | nM | - |
| CHEMBL1163826 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1164098 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1163274 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1165453 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1165153 | — | IC50 | > | 100000.0 | nM | - |