Assay Detail
Functional
CHEMBL1273701
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Antiprotozoal activity against Trichomonas vaginalis
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trichomonas vaginalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Towards a systematic characterization of the antiprotozoal activity landscape of benzimidazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.10 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL227370 | — | — | 1 | 8.70 |
| CHEMBL1269197 | — | — | 1 | 6.70 |
| CHEMBL389272 | — | — | 1 | 6.66 |
| CHEMBL226656 | — | — | 1 | 6.52 |
| CHEMBL226920 | — | — | 1 | 6.24 |
| CHEMBL1269198 | — | — | 1 | 5.59 |
| CHEMBL226921 | — | — | 1 | 5.00 |
| CHEMBL1270445 | — | — | 1 | 4.97 |
| CHEMBL1270444 | — | — | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL227370 | — | IC50 | = | 1.995 | nM | 8.70 |
| CHEMBL1269197 | — | IC50 | = | 199.53 | nM | 6.70 |
| CHEMBL389272 | — | IC50 | = | 218.78 | nM | 6.66 |
| CHEMBL226656 | — | IC50 | = | 302.0 | nM | 6.52 |
| CHEMBL226920 | — | IC50 | = | 575.44 | nM | 6.24 |
| CHEMBL1269198 | — | IC50 | = | 2570.4 | nM | 5.59 |
| CHEMBL226921 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1270445 | — | IC50 | = | 10715.19 | nM | 4.97 |
| CHEMBL1270444 | — | IC50 | = | 29512.09 | nM | 4.53 |