Assay Detail
Binding
CHEMBL1285513
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of telomerase in human SGC7901 cells by TRAP assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | SGC-7901 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3,4-oxadiazole moiety as potential antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.54 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1278128 | — | — | 1 | 5.64 |
| CHEMBL284328 | HOMIDIUM BROMIDE | 2.0 | 1 | 5.60 |
| CHEMBL1276872 | — | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1278128 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL284328 | HOMIDIUM BROMIDE | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL1276872 | — | IC50 | = | 4200.0 | nM | 5.38 |