Assay Detail
Functional
CHEMBL1614339
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Luminescent Cell-Based Dose Titration Retest Counterscreen to Identify Proteasome Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1910 (Primary HTS), 1971 (Project Summary)]
1154
Total Activities
1154
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1154 | 4.64 | 6.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1526189 | — | — | 1 | 6.07 |
| CHEMBL1305428 | — | — | 1 | 5.64 |
| CHEMBL1388351 | — | — | 1 | 5.62 |
| CHEMBL1333738 | — | — | 1 | 5.60 |
| CHEMBL1475128 | — | — | 1 | 5.59 |
| CHEMBL1459709 | — | — | 1 | 5.50 |
| CHEMBL1568996 | — | — | 1 | 5.46 |
| CHEMBL528694 | — | — | 1 | 5.46 |
| CHEMBL1511713 | — | — | 1 | 5.41 |
| CHEMBL1984190 | — | — | 1 | 5.40 |
| CHEMBL1977678 | — | — | 1 | 5.39 |
| CHEMBL1538056 | — | — | 1 | 5.36 |
| CHEMBL1583414 | — | — | 1 | 5.36 |
| CHEMBL1430053 | — | — | 1 | 5.33 |
| CHEMBL1412396 | — | — | 1 | 5.30 |
| CHEMBL1300836 | — | — | 1 | 5.30 |
| CHEMBL3199020 | — | — | 1 | 5.29 |
| CHEMBL3213546 | — | — | 1 | 5.28 |
| CHEMBL3193510 | — | — | 1 | 5.25 |
| CHEMBL1320983 | — | — | 1 | 5.24 |
| CHEMBL1389695 | — | — | 1 | 5.24 |
| CHEMBL1335843 | — | — | 1 | 5.23 |
| CHEMBL3196374 | — | — | 1 | 5.22 |
| CHEMBL1414754 | — | — | 1 | 5.22 |
| CHEMBL104732 | — | — | 1 | 5.21 |
| CHEMBL3197396 | — | — | 1 | 5.20 |
| CHEMBL1395615 | — | — | 1 | 5.20 |
| CHEMBL3208905 | — | — | 1 | 5.19 |
| CHEMBL3192817 | — | — | 1 | 5.19 |
| CHEMBL1982774 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1526189 | — | EC50 | = | 850.0 | nM | 6.07 |
| CHEMBL1305428 | — | EC50 | = | 2273.0 | nM | 5.64 |
| CHEMBL1388351 | — | EC50 | = | 2394.0 | nM | 5.62 |
| CHEMBL1333738 | — | EC50 | = | 2489.0 | nM | 5.60 |
| CHEMBL1475128 | — | EC50 | = | 2553.0 | nM | 5.59 |
| CHEMBL1459709 | — | EC50 | = | 3133.0 | nM | 5.50 |
| CHEMBL1568996 | — | EC50 | = | 3494.0 | nM | 5.46 |
| CHEMBL528694 | — | EC50 | = | 3447.0 | nM | 5.46 |
| CHEMBL1511713 | — | EC50 | = | 3937.0 | nM | 5.41 |
| CHEMBL1984190 | — | EC50 | = | 4022.0 | nM | 5.40 |
| CHEMBL1977678 | — | EC50 | = | 4069.0 | nM | 5.39 |
| CHEMBL1583414 | — | EC50 | = | 4394.0 | nM | 5.36 |
| CHEMBL1538056 | — | EC50 | = | 4399.0 | nM | 5.36 |
| CHEMBL1430053 | — | EC50 | = | 4687.0 | nM | 5.33 |
| CHEMBL1300836 | — | EC50 | = | 5026.0 | nM | 5.30 |
| CHEMBL1412396 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3199020 | — | EC50 | = | 5155.0 | nM | 5.29 |
| CHEMBL3213546 | — | EC50 | = | 5271.0 | nM | 5.28 |
| CHEMBL3193510 | — | EC50 | = | 5670.0 | nM | 5.25 |
| CHEMBL1389695 | — | EC50 | = | 5814.0 | nM | 5.24 |
| CHEMBL1320983 | — | EC50 | = | 5782.0 | nM | 5.24 |
| CHEMBL1335843 | — | EC50 | = | 5872.0 | nM | 5.23 |
| CHEMBL3196374 | — | EC50 | = | 5987.0 | nM | 5.22 |
| CHEMBL1414754 | — | EC50 | = | 6078.0 | nM | 5.22 |
| CHEMBL104732 | — | EC50 | = | 6118.0 | nM | 5.21 |
| CHEMBL1395615 | — | EC50 | = | 6294.0 | nM | 5.20 |
| CHEMBL3197396 | — | EC50 | = | 6368.0 | nM | 5.20 |
| CHEMBL3208905 | — | EC50 | = | 6488.0 | nM | 5.19 |
| CHEMBL3192817 | — | EC50 | = | 6390.0 | nM | 5.19 |
| CHEMBL1982774 | — | EC50 | = | 6413.0 | nM | 5.19 |
| CHEMBL1311879 | — | EC50 | = | 6465.0 | nM | 5.19 |
| CHEMBL1506697 | — | EC50 | = | 6643.0 | nM | 5.18 |
| CHEMBL1519731 | — | EC50 | = | 6575.0 | nM | 5.18 |
| CHEMBL1991779 | — | EC50 | = | 6967.0 | nM | 5.16 |
| CHEMBL546170 | — | EC50 | = | 6910.0 | nM | 5.16 |
| CHEMBL1508694 | — | EC50 | = | 6919.0 | nM | 5.16 |
| CHEMBL1522279 | — | EC50 | = | 6867.0 | nM | 5.16 |
| CHEMBL1462710 | — | EC50 | = | 7102.0 | nM | 5.15 |
| CHEMBL1595632 | — | EC50 | = | 7123.0 | nM | 5.15 |
| CHEMBL1323308 | — | EC50 | = | 7014.0 | nM | 5.15 |
| CHEMBL1505604 | — | EC50 | = | 7184.0 | nM | 5.14 |
| CHEMBL1979295 | — | EC50 | = | 7226.0 | nM | 5.14 |
| CHEMBL1993190 | — | EC50 | = | 7287.0 | nM | 5.14 |
| CHEMBL1381322 | — | EC50 | = | 7181.0 | nM | 5.14 |
| CHEMBL1377376 | — | EC50 | = | 7303.0 | nM | 5.14 |
| CHEMBL1503145 | — | EC50 | = | 7405.0 | nM | 5.13 |
| CHEMBL1384998 | — | EC50 | = | 7409.0 | nM | 5.13 |
| CHEMBL1977570 | — | EC50 | = | 7474.0 | nM | 5.13 |
| CHEMBL1987472 | — | EC50 | = | 7332.0 | nM | 5.13 |
| CHEMBL3191962 | — | EC50 | = | 7383.0 | nM | 5.13 |