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Compound Detail

CHEMBL3192817

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Cc1cccc(/C=N/NC(=O)c2ccc3c(c2)OCCO3)c1O

Basic Information

ChEMBL ID CHEMBL3192817
Phase Preclinical
Structure Type MOL
InChI Key GDZBUSRFBADTGY-VCHYOVAHSA-N
4
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

312.3
MW (Da)
2.24
ALogP
5
HBA
2
HBD
80.2
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H16N2O4
MW 312.32
Aromatic Rings 2
Heavy Atoms 23
NP-Likeness -1.36

Activity Summary

EC50 5 meas. best 5.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Streptococcus sp. 'group A'
CHEMBL612389
EC50 5.52 5.52 3049.0 1
Streptokinase A
CHEMBL1293228
EC50 5.36 5.36 4393.0 1
Unchecked
CHEMBL612545
EC50 5.19 4.685 6390.0 2
Streptococcus
CHEMBL612313
EC50 5.17 5.17 6823.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine