Streptokinase A · SINGLE PROTEIN · Streptococcus pyogenes serotype M1
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P10520. Use UniProt P10520 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10520 as the stable identity anchor, then attach disease evidence before program review.
Streptokinase A
Review this target as Streptokinase A, mapped to UniProt P10520. Sequence length is 440 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Streptokinase A as ChEMBL target CHEMBL1293228, mapped to UniProt P10520. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Streptokinase A is the right protein anchor across sources, using UniProt P10520 as the stable mapping.
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| Preferred Name | Streptokinase A |
| Target Type | SINGLE PROTEIN |
| Organism | Streptococcus pyogenes serotype M1 |
| UniProt | P10520 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Streptokinase A |
| UniProt Accession | P10520 |
| Component Type | Protein |
| Sequence Length | 440 aa |
Streptokinase A
Review this target as Streptokinase A, mapped to UniProt P10520. Sequence length is 440 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2094567 | 7.2 | EC50 | 63.0 | Preclinical |
| CHEMBL278255 | 7.19 | EC50 | 64.0 | Clinical |
| CHEMBL2146063 | 7.19 | EC50 | 65.0 | Approved |
| CHEMBL1422078 | 7.16 | EC50 | 69.0 | Preclinical |
| CHEMBL1427178 | 7.13 | EC50 | 74.0 | Preclinical |
| CHEMBL1593888 | 7.13 | EC50 | 74.0 | Preclinical |
| CHEMBL1542263 | 7.11 | EC50 | 78.0 | Preclinical |
| CHEMBL12131 | 7.09 | EC50 | 82.0 | Clinical |
| CHEMBL1306986 | 7.09 | EC50 | 81.0 | Preclinical |
| CHEMBL1563791 | 7.05 | EC50 | 90.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 2,941 | 5.3 |
| organism-based format | 2 | 0 | — |