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Compound Detail

CHEMBL1984190

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Oc1ccccc1/C=N/Nc1nc2ccccc2o1

Basic Information

ChEMBL ID CHEMBL1984190
Phase Preclinical
Structure Type MOL
InChI Key VEWGEYARSOOEBT-OQLLNIDSSA-N
4
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

253.3
MW (Da)
2.98
ALogP
5
HBA
2
HBD
70.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C14H11N3O2
MW 253.26
Aromatic Rings 3
Heavy Atoms 19
NP-Likeness -1.18

Activity Summary

EC50 5 meas. best 5.72

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Streptococcus sp. 'group A'
CHEMBL612389
EC50 5.72 5.72 1896.0 1
Streptokinase A
CHEMBL1293228
EC50 5.62 5.62 2420.0 1
Unchecked
CHEMBL612545
EC50 5.53 5.465 2925.0 2
Streptococcus
CHEMBL612313
EC50 5.38 5.38 4170.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine