Assay Detail
Binding
CHEMBL1614363
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study. (Class of assay: confirmatory) [Related pubchem assays: 621, 432 ]
141
Total Activities
141
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 141 | 5.41 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1271764 | — | — | 1 | 6.44 |
| CHEMBL1269202 | — | — | 1 | 6.38 |
| CHEMBL1272154 | — | — | 1 | 6.33 |
| CHEMBL1323507 | — | — | 1 | 6.25 |
| CHEMBL1272100 | — | — | 1 | 6.25 |
| CHEMBL1271495 | — | — | 1 | 6.23 |
| CHEMBL1531647 | — | — | 1 | 6.01 |
| CHEMBL1484952 | — | — | 1 | 6.00 |
| CHEMBL1272047 | — | — | 1 | 5.94 |
| CHEMBL1598121 | — | — | 1 | 5.94 |
| CHEMBL1272210 | — | — | 1 | 5.90 |
| CHEMBL1272263 | — | — | 1 | 5.90 |
| CHEMBL1272048 | — | — | 1 | 5.88 |
| CHEMBL1334163 | — | — | 1 | 5.85 |
| CHEMBL1370758 | — | — | 1 | 5.83 |
| CHEMBL1271993 | — | — | 1 | 5.82 |
| CHEMBL1328468 | — | — | 1 | 5.79 |
| CHEMBL1519581 | — | — | 1 | 5.79 |
| CHEMBL1272313 | — | — | 1 | 5.79 |
| CHEMBL1271994 | — | — | 1 | 5.78 |
| CHEMBL1331084 | — | — | 1 | 5.77 |
| CHEMBL1567695 | — | — | 1 | 5.77 |
| CHEMBL1451200 | — | — | 1 | 5.72 |
| CHEMBL1271825 | — | — | 1 | 5.67 |
| CHEMBL1417970 | — | — | 1 | 5.67 |
| CHEMBL1271881 | — | — | 1 | 5.67 |
| CHEMBL1359585 | — | — | 1 | 5.64 |
| CHEMBL1271765 | — | — | 1 | 5.61 |
| CHEMBL1329808 | — | — | 1 | 5.59 |
| CHEMBL1271766 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1271764 | — | IC50 | = | 362.0 | nM | 6.44 |
| CHEMBL1269202 | — | IC50 | = | 419.0 | nM | 6.38 |
| CHEMBL1272154 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL1323507 | — | IC50 | = | 565.0 | nM | 6.25 |
| CHEMBL1272100 | — | IC50 | = | 556.0 | nM | 6.25 |
| CHEMBL1271495 | — | IC50 | = | 594.0 | nM | 6.23 |
| CHEMBL1531647 | — | IC50 | = | 979.0 | nM | 6.01 |
| CHEMBL1484952 | — | IC50 | = | 999.0 | nM | 6.00 |
| CHEMBL1598121 | — | IC50 | = | 1150.0 | nM | 5.94 |
| CHEMBL1272047 | — | IC50 | = | 1160.0 | nM | 5.94 |
| CHEMBL1272263 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL1272210 | — | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL1272048 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL1334163 | — | IC50 | = | 1420.0 | nM | 5.85 |
| CHEMBL1370758 | — | IC50 | = | 1490.0 | nM | 5.83 |
| CHEMBL1271993 | — | IC50 | = | 1510.0 | nM | 5.82 |
| CHEMBL1328468 | — | IC50 | = | 1630.0 | nM | 5.79 |
| CHEMBL1519581 | — | IC50 | = | 1640.0 | nM | 5.79 |
| CHEMBL1272313 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL1271994 | — | IC50 | = | 1670.0 | nM | 5.78 |
| CHEMBL1331084 | — | IC50 | = | 1690.0 | nM | 5.77 |
| CHEMBL1567695 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1451200 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL1417970 | — | IC50 | = | 2160.0 | nM | 5.67 |
| CHEMBL1271825 | — | IC50 | = | 2160.0 | nM | 5.67 |
| CHEMBL1271881 | — | IC50 | = | 2150.0 | nM | 5.67 |
| CHEMBL1359585 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL1271765 | — | IC50 | = | 2440.0 | nM | 5.61 |
| CHEMBL1329808 | — | IC50 | = | 2590.0 | nM | 5.59 |
| CHEMBL1271766 | — | IC50 | = | 2620.0 | nM | 5.58 |
| CHEMBL1531467 | — | IC50 | = | 3410.0 | nM | 5.47 |
| CHEMBL1399711 | — | IC50 | = | 3850.0 | nM | 5.42 |
| CHEMBL1414442 | — | IC50 | = | 4050.0 | nM | 5.39 |
| CHEMBL1271494 | — | IC50 | = | 4070.0 | nM | 5.39 |
| CHEMBL1325110 | — | IC50 | = | 4460.0 | nM | 5.35 |
| CHEMBL1364744 | — | IC50 | = | 4680.0 | nM | 5.33 |
| CHEMBL1272155 | — | IC50 | = | 4950.0 | nM | 5.30 |
| CHEMBL1449204 | — | IC50 | = | 5360.0 | nM | 5.27 |
| CHEMBL1346587 | — | IC50 | = | 5390.0 | nM | 5.27 |
| CHEMBL1272049 | — | IC50 | = | 5630.0 | nM | 5.25 |
| CHEMBL1450886 | — | IC50 | = | 6780.0 | nM | 5.17 |
| CHEMBL1271883 | — | IC50 | = | 6790.0 | nM | 5.17 |
| CHEMBL1489550 | — | IC50 | = | 6960.0 | nM | 5.16 |
| CHEMBL1321179 | — | IC50 | = | 8470.0 | nM | 5.07 |
| CHEMBL1271823 | — | IC50 | = | 8740.0 | nM | 5.06 |
| CHEMBL1372840 | — | IC50 | = | 8850.0 | nM | 5.05 |
| CHEMBL1272209 | — | IC50 | = | 9570.0 | nM | 5.02 |
| CHEMBL1528528 | — | IC50 | = | 9680.0 | nM | 5.01 |
| CHEMBL1360686 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL1272099 | — | IC50 | = | 10500.0 | nM | 4.98 |