Assay Detail
Functional
CHEMBL1614403
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Fluorescent HTS Cytotoxicity/Cell viability assay (HT1080 cells). (Class of assay: confirmatory) [Related pubchem assays: 618, 773 ]
270
Total Activities
270
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-1080 |
| Category | confirmatory |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 270 | 4.69 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1415517 | — | — | 1 | 5.19 |
| CHEMBL1539572 | — | — | 1 | 4.95 |
| CHEMBL1445776 | — | — | 1 | 4.91 |
| CHEMBL1429929 | — | — | 1 | 4.85 |
| CHEMBL1530797 | — | — | 1 | 4.84 |
| CHEMBL1493429 | — | — | 1 | 4.84 |
| CHEMBL1342109 | — | — | 1 | 4.83 |
| CHEMBL1490887 | — | — | 1 | 4.83 |
| CHEMBL1558159 | — | — | 1 | 4.82 |
| CHEMBL1491676 | — | — | 1 | 4.82 |
| CHEMBL585656 | — | — | 1 | 4.81 |
| CHEMBL1498959 | — | — | 1 | 4.76 |
| CHEMBL1535546 | — | — | 1 | 4.75 |
| CHEMBL1309232 | — | — | 1 | 4.73 |
| CHEMBL1502512 | — | — | 1 | 4.70 |
| CHEMBL1527186 | — | — | 1 | 4.69 |
| CHEMBL1386649 | — | — | 1 | 4.69 |
| CHEMBL1527447 | — | — | 1 | 4.69 |
| CHEMBL379179 | — | — | 1 | 4.69 |
| CHEMBL1378118 | — | — | 1 | 4.68 |
| CHEMBL1541834 | — | — | 1 | 4.65 |
| CHEMBL1389449 | — | — | 1 | 4.65 |
| CHEMBL146525 | — | — | 1 | 4.64 |
| CHEMBL1596406 | — | — | 1 | 4.59 |
| CHEMBL547833 | — | — | 1 | 4.59 |
| CHEMBL1329235 | — | — | 1 | 4.55 |
| CHEMBL1428003 | — | — | 1 | 4.52 |
| CHEMBL1352955 | — | — | 1 | 4.52 |
| CHEMBL1314042 | — | — | 1 | 4.51 |
| CHEMBL1412795 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1415517 | — | EC50 | = | 6410.0 | nM | 5.19 |
| CHEMBL1539572 | — | EC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL1445776 | — | EC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL1429929 | — | EC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL1493429 | — | EC50 | = | 14600.0 | nM | 4.84 |
| CHEMBL1530797 | — | EC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL1342109 | — | EC50 | = | 14800.0 | nM | 4.83 |
| CHEMBL1490887 | — | EC50 | = | 14700.0 | nM | 4.83 |
| CHEMBL1491676 | — | EC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL1558159 | — | EC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL585656 | — | EC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL1498959 | — | EC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL1535546 | — | EC50 | = | 17800.0 | nM | 4.75 |
| CHEMBL1309232 | — | EC50 | = | 18800.0 | nM | 4.73 |
| CHEMBL1502512 | — | EC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL1386649 | — | EC50 | = | 20400.0 | nM | 4.69 |
| CHEMBL1527186 | — | EC50 | = | 20600.0 | nM | 4.69 |
| CHEMBL1527447 | — | EC50 | = | 20300.0 | nM | 4.69 |
| CHEMBL379179 | — | EC50 | = | 20300.0 | nM | 4.69 |
| CHEMBL1378118 | — | EC50 | = | 20700.0 | nM | 4.68 |
| CHEMBL1541834 | — | EC50 | = | 22200.0 | nM | 4.65 |
| CHEMBL1389449 | — | EC50 | = | 22600.0 | nM | 4.65 |
| CHEMBL146525 | — | EC50 | = | 22800.0 | nM | 4.64 |
| CHEMBL547833 | — | EC50 | = | 25700.0 | nM | 4.59 |
| CHEMBL1596406 | — | EC50 | = | 25700.0 | nM | 4.59 |
| CHEMBL1329235 | — | EC50 | = | 27900.0 | nM | 4.55 |
| CHEMBL1352955 | — | EC50 | = | 29900.0 | nM | 4.52 |
| CHEMBL1428003 | — | EC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL1314042 | — | EC50 | = | 30800.0 | nM | 4.51 |
| CHEMBL1412795 | — | EC50 | = | 33800.0 | nM | 4.47 |
| CHEMBL1467876 | — | EC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL1464853 | — | EC50 | = | 45900.0 | nM | 4.34 |
| CHEMBL532504 | — | EC50 | = | 51500.0 | nM | 4.29 |
| CHEMBL1308451 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1603662 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1603691 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1427801 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1456099 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1450780 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1365191 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1347687 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1426911 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1612106 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1416853 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL482116 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1320414 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1978424 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1521960 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1504592 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL1307028 | — | EC50 | > | 50000.0 | nM | - |