Compound Detail
CHEMBL1541834
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1541834 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GINDUKKWVPOXHU-UHFFFAOYSA-N |
10
Targets
24
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
324.8
MW (Da)
4.15
ALogP
3
HBA
1
HBD
36.4
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 16 meas. best 6.15
IC50 8 meas. best 6.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MES-SA/Dx5 CHEMBL613827 | IC50 | 6.57 | 6.275 | 270.0 | 2 |
| Unchecked CHEMBL612545 | EC50 | 6.15 | 5.5583 | 712.0 | 6 |
| ATP-dependent molecular chaperone HSP82 CHEMBL1293251 | EC50 | 6.07 | 5.695 | 849.0 | 2 |
| MES-SA CHEMBL614343 | IC50 | 5.74 | 5.725 | 1810.0 | 2 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.67 | 5.67 | 2153.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.53 | 5.53 | 2948.0 | 1 |
| Nucleic Acid CHEMBL345 | EC50 | 5.24 | 5.24 | 5810.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.13 | 4.9175 | 7360.0 | 4 |
| BJ CHEMBL614358 | EC50 | 5.07 | 5.0333 | 8454.0 | 3 |
| Streptococcus CHEMBL612313 | EC50 | 5.03 | 5.03 | 9326.0 | 1 |
| HT-1080 CHEMBL614580 | EC50 | 4.65 | 4.65 | 22200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35613553 | 10.1021/acs.jmedchem.2c00076 | MES-SA | 2 |
| 35613553 | 10.1021/acs.jmedchem.2c00076 | Unchecked | 2 |
| 35613553 | 10.1021/acs.jmedchem.2c00076 | MES-SA/Dx5 | 2 |
Data from ChEMBL 36 via Core Engine