Assay Detail
Functional
CHEMBL1614532
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: LPS induced NF-kB in THP.1 cells. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1266, AID1269, AID1270, AID1271, AID1280, AID1281, AID1282, AID1283, AID1287, AID1289, AID1290, AID1291, AID1292, AID1293, AID1294, AID1295, AID1299, AID1302, AID1364, AID1365, AID1366, AID1367, AID1368, AID1370, AID1371, AID1372, AID1373, AID1374, AID1375, AID1384, AID465]
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | THP-1 |
| Category | confirmatory |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.24 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1427791 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1427791 | — | EC50 | = | 5741.0 | nM | 5.24 |