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Assay Detail

CHEMBL1640063

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Functional
Antiviral activity against KJ56-1 Bovine rotavirus G8P[7] infected in african green monkey TF-104 cells after 72 hrs by virucidal assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bovine rotavirus
Cell Type TF-104
Confidence 1 — Organism
Curated By Autocuration

Publication

In vitro anti-rotavirus activity of polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.
Kwon HJ, Kim HH, Ryu YB, Kim JH, Jeong HJ, Lee SW, Chang JS, Cho KO, Rho MC, Park SJ, Lee WS.
Bioorg Med Chem (2010) 18 : 7668 -7674
PubMed 20850329 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 5 4.57 4.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1630857 GLYASPERIN C 1 4.83
CHEMBL600185 LICOFLAVONOL 1 4.81
CHEMBL1563332 GLYASPERIN D 1 4.75
CHEMBL611368 LICOCOUMARONE 1 4.42
CHEMBL132535 GLYCYRIN 1 4.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1630857 GLYASPERIN C EC50 = 14700.0 nM 4.83
CHEMBL600185 LICOFLAVONOL EC50 = 15500.0 nM 4.81
CHEMBL1563332 GLYASPERIN D EC50 = 17600.0 nM 4.75
CHEMBL611368 LICOCOUMARONE EC50 = 37800.0 nM 4.42
CHEMBL132535 GLYCYRIN EC50 = 88100.0 nM 4.05