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Assay Detail

CHEMBL1660105

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitrypanosomal activity against bloodstream forms of Trypanosoma cruzi Y after 24 hrs by light microscopy in presence of 96% mouse blood
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Autocuration

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Batista Dda G, Batista MM, de Oliveira GM, do Amaral PB, Lannes-Vieira J, Britto CC, Junqueira A, Lima MM, Romanha AJ, Sales Junior PA, Stephens CE, Boykin DW, Soeiro Mde N.
Antimicrob Agents Chemother (2010) 54 : 2940 -2952
PubMed 20457822 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.22 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1275764 1 7.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1275764 IC50 = 60.0 nM 7.22