Assay Detail
Binding
CHEMBL1663955
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement radioligand form dopamine D2 receptor in rat striatum by liquid scintillation counting
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Striatum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.66 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 8.68 |
| CHEMBL1036 | HYDROXYHALOPERIDOL | — | 1 | 6.63 |
| CHEMBL1649601 | — | — | 1 | - |
| CHEMBL1469 | PHENYLBUTANOIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL1036 | HYDROXYHALOPERIDOL | Ki | = | 232.0 | nM | 6.63 |
| CHEMBL1649601 | — | Ki | > | 5000.0 | nM | - |
| CHEMBL1469 | PHENYLBUTANOIC ACID | Ki | - | — | - |