Assay Detail
Functional
CHEMBL1676508
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Antifungal activity against 5 x 10'6 CFU/ml Trichophyton quinckeanum B68683 by resazurin based fluorimetry assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trichophyton quinckeanum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.38 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL822 | TERBINAFINE | 4.0 | 1 | 8.00 |
| CHEMBL91 | MICONAZOLE | 4.0 | 1 | 6.10 |
| CHEMBL175633 | PRAMICONAZOLE | 2.0 | 1 | 5.87 |
| CHEMBL64391 | ITRACONAZOLE | 4.0 | 1 | 5.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL822 | TERBINAFINE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL91 | MICONAZOLE | IC50 | = | 790.0 | nM | 6.10 |
| CHEMBL175633 | PRAMICONAZOLE | IC50 | = | 1340.0 | nM | 5.87 |
| CHEMBL64391 | ITRACONAZOLE | IC50 | = | 2930.0 | nM | 5.53 |