Assay Detail
Functional
CHEMBL1685452
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma brucei 427
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL536047 | — | — | 1 | 6.52 |
| CHEMBL1684448 | — | — | 1 | 6.52 |
| CHEMBL1684447 | — | — | 1 | 6.52 |
| CHEMBL1684446 | HUPRINE X HYDROCHLORIDE | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL536047 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1684448 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1684447 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1684446 | HUPRINE X HYDROCHLORIDE | IC50 | = | 300.0 | nM | 6.52 |