Assay Detail
Binding
CHEMBL1686598
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]testosterone from Sprague-Dawley rat AR by liquid scintillation counting
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.89 | 8.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | 2.0 | 1 | 8.51 |
| CHEMBL1684194 | — | — | 1 | 7.89 |
| CHEMBL409 | BICALUTAMIDE | 4.0 | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL1684194 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL409 | BICALUTAMIDE | IC50 | = | 54.0 | nM | 7.27 |