Assay Detail
ADMET
CHEMBL1767686
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765107 | — | — | 1 | 5.70 |
| CHEMBL1766759 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765107 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL1766759 | — | IC50 | > | 100000.0 | nM | - |