Assay Detail
Functional
CHEMBL1772729
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Cytotoxicity against human A2780 cells by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of 5(6)-dihydro-OSW-1 analogs bearing three kinds of disaccharides linking at 15-hydroxy and their antitumor activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.25 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1770264 | — | — | 1 | 6.26 |
| CHEMBL507001 | DIOSCIN | — | 1 | 6.24 |
| CHEMBL1771601 | — | — | 1 | - |
| CHEMBL1771602 | — | — | 1 | - |
| CHEMBL1770259 | — | — | 1 | - |
| CHEMBL1770260 | — | — | 1 | - |
| CHEMBL1770261 | — | — | 1 | - |
| CHEMBL1770262 | — | — | 1 | - |
| CHEMBL1770263 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1770264 | — | IC50 | = | 545.0 | nM | 6.26 |
| CHEMBL507001 | DIOSCIN | IC50 | = | 581.0 | nM | 6.24 |
| CHEMBL1771601 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1771602 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1770259 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1770260 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1770261 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1770262 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1770263 | — | IC50 | > | 10000.0 | nM | - |